Reversal of clonidine induced miosis by the alpha 2-adrenoreceptor antagonist RX 781094.
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چکیده
منابع مشابه
Effect of Centrally Acting a-Adrenergic Agonists
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Large doses of the imidazoline alpha 2 adrenoreceptor agonist clonidine aggravate ethanol-induced gastric lesions. The alpha 2 adrenoceptor antagonist phentolamine, the opioid antagonist naloxone and the H2 antagonist cimetidine do not prevent this action of clonidine suggesting that it is not mediated by alpha 2, opioid or H2 receptors. Further, like clonidine, high doses of phentolamine and c...
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Alpha 2-adrenoreceptor status in obsessive-compulsive disorder.
Ten patients with obsessive-compulsive disorder (OCD) and 13 normal control subjects received intravenous infusions of 2 X 10(-6) g/kg of clonidine and normal saline on separate days. Responses to the drug relating to plasma growth hormone (GH), 3-methoxy-4-hydroxyphenylglycol (MHPG), heart rate, blood pressure, and several symptoms were determined. Additionally, platelet alpha 2-adrenoreceptor...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1982
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1982.tb04941.x